Routine Drugs for Pregnancy: What They Are and Why You Need Them

Caleb Ihuarulam

Caleb Ihuarulam

Once you register for antenatal care in Nigeria, your doctor or midwife will usually start you on a set of “routine drugs”. These are not treatments for an illness. They are supplements and preventive medicines that fill nutritional gaps and protect you and your baby from common problems like anaemia, malaria and birth defects.

This guide explains the routine drugs for pregnancy, what each one does, when it is usually started and the foods that support them. Your doctor will tailor the exact list and doses to you, so always follow their prescription.

Why routine drugs matter in pregnancy

Pregnancy increases your need for several nutrients, especially folate, iron and calcium. A balanced diet is the foundation, but food alone often does not provide enough, particularly if you have nausea and vomiting, are carrying twins, or had low nutrient stores before pregnancy. Routine supplements close that gap.

List of routine drugs for pregnancy

Most pregnant women in Nigeria are given some or all of these:

  • Folic acid
  • Iron (often ferrous sulphate or ferrous fumarate), sometimes combined with folic acid
  • Calcium, usually from the second half of pregnancy
  • A prenatal multivitamin, which may include vitamin D and other nutrients
  • Malaria prevention (IPTp with sulfadoxine-pyrimethamine), from the second trimester
  • Tetanus-diphtheria vaccination
  • Deworming medicine, after the first trimester in some clinics

Here is what each one does.

1. Folic acid

Folic acid (vitamin B9) is essential for your baby’s developing brain and spinal cord. Taking it lowers the risk of neural tube defects such as spina bifida, which form in the first weeks of pregnancy, often before a woman knows she is pregnant.

  • When: Ideally from before conception and through at least the first trimester. Many clinics continue it throughout pregnancy, often combined with iron.
  • Usual dose: 400 micrograms (mcg) a day. Women at higher risk, for example those with diabetes, sickle cell disease, epilepsy or a previous baby with a neural tube defect, may be prescribed a higher dose.
  • Food sources: Dark green leafy vegetables such as ugwu and spinach, beans, oranges and fortified cereals.

2. Iron

Your blood volume rises sharply in pregnancy, and your baby builds its own iron stores. Without enough iron you can develop anaemia, which causes tiredness and breathlessness and raises the risk of preterm birth and low birth weight.

  • When: The World Health Organization (WHO) recommends daily iron and folic acid supplements throughout pregnancy.
  • Usual dose: WHO recommends 30–60 mg of elemental iron daily. Your doctor may prescribe more if tests show you are anaemic.
  • Tips: Take iron with water or orange juice, as vitamin C helps absorption. Avoid taking it with tea, coffee or milk, which reduce absorption. Constipation and dark stools are common side effects; tell your doctor if they bother you.
  • Food sources: Red meat, liver (in moderation), fish, beans, and leafy greens.

3. Calcium

Calcium builds your baby’s bones and teeth. Where diets are low in calcium, supplements also help lower the risk of pre-eclampsia, a dangerous rise in blood pressure in pregnancy.

  • When: Usually from about 20 weeks until delivery.
  • Usual dose: For populations with low calcium intake, WHO recommends 1.5–2.0 g of elemental calcium a day, split into doses.
  • Tip: Take calcium and iron at different times of day, as calcium reduces iron absorption.
  • Food sources: Milk, yoghurt, cheese, small fish eaten with bones such as sardines and crayfish, and green vegetables.

4. Prenatal multivitamins, vitamin D and omega-3

Many women take a prenatal multivitamin that combines several nutrients. Two worth knowing about:

  • Vitamin D helps your body use calcium for your baby’s bones. Most people get enough from sunlight, but your doctor may recommend a supplement if you cover your skin, spend most of your time indoors or have low levels.
  • Omega-3 fatty acids (DHA) support your baby’s brain and eye development. Oily fish such as sardines and mackerel (titus) are good sources. Supplements are optional; ask your doctor.

Do not take extra vitamin A supplements or fish liver oil on top of a prenatal vitamin unless your doctor advises it. Too much vitamin A can harm your baby.

5. Malaria prevention (IPTp)

Malaria in pregnancy can cause severe anaemia in the mother, miscarriage, and low birth weight. In Nigeria, pregnant women are given intermittent preventive treatment (IPTp) with sulfadoxine-pyrimethamine (SP), starting in the second trimester and repeated at antenatal visits, usually monthly, until delivery.

Also sleep under an insecticide-treated net every night. If you develop a fever, see a doctor promptly. Do not treat it yourself.

6. Tetanus vaccination and deworming

Tetanus-diphtheria (Td) vaccination protects both you and your newborn from tetanus. The number of doses you need depends on your previous vaccinations.

Deworming with medicines such as albendazole or mebendazole may be given after the first trimester in areas where intestinal worms are common, to help prevent anaemia.

Safety tips for routine drugs

  • Take only what your doctor or midwife prescribes, at the dose prescribed.
  • Do not buy extra supplements, herbal mixtures or agbo without asking first.
  • If you miss a dose, take it when you remember, unless it is nearly time for the next one. Do not double up.
  • Keep iron tablets away from children. Iron overdose is dangerous for young children.
  • Bring all your medicines to antenatal visits so your doctor can review them.

Some medicines are not safe in pregnancy. Read drugs to avoid during pregnancy, and learn more about why antenatal care matters and the best fruits and vegetables to eat during pregnancy.

Related: Benefits of Breastfeeding for Baby and Mother

Frequently asked questions

What are routine drugs for pregnancy?
They are the supplements and preventive medicines given to most pregnant women at antenatal care: usually folic acid, iron, calcium, a prenatal multivitamin, malaria prevention (IPTp-SP) and tetanus vaccination.

When should I start taking folic acid?
Ideally before you start trying to get pregnant, and as soon as you know you are pregnant if you have not already started.

Can I take routine drugs in the first month of pregnancy?
Folic acid is especially important in the first month. Other routine drugs, such as malaria prevention, are started later in pregnancy. Your doctor will tell you when to start each one.

Are routine drugs covered by my HMO?
It depends on your plan. Read does HMO cover pregnancy? to understand maternity cover and waiting periods.

Planning ahead? See the best HMO plans for families in Nigeria.

This article is for general information and does not replace advice from your doctor or midwife.

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Caleb Ihuarulam

Caleb Ihuarulam

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